PRF Pre & Post Care Instructions

Platelet-Rich Fibrin (PRF) is an autologous regenerative treatment prepared from a small sample of your own blood.

Your blood is processed to concentrate platelets within a fibrin-rich matrix containing naturally occurring growth factors and cellular components involved in tissue repair and signaling. PRF may be used as a stand-alone injectable treatment or incorporated into a personalized regenerative treatment plan.

PRF may be used with the goal of supporting:

Overall skin quality

Skin texture

Elasticity

Fine lines and crepey-looking skin

Periorbital rejuvenation

The skin’s natural regenerative processes

Results are gradual and vary between patients. Current evidence is promising but does not support guaranteed improvement in every skin concern.

Before Your Appointment

1. Arrive with a clean treatment area.
If possible, arrive without makeup, creams, serums, sunscreen, or other skincare products on the areas being treated.

2. Tell your provider about all medications and supplements.
Please disclose prescription medications, aspirin, NSAIDs, anticoagulants, vitamins, herbal products, fish oil, vitamin E, and other supplements.

Do not stop any prescribed medication, aspirin, anticoagulant, or medically recommended medication unless the clinician who prescribed it has specifically told you it is safe to do so.

3. Tell us about your medical history.
Please notify your provider before treatment if you:

  • are pregnant, planning pregnancy, or breastfeeding

  • have allergies or previous reactions to dermal fillers, lidocaine, or injectable products

  • have an autoimmune condition or significant medical history

  • have an active infection, rash, acne lesion, wound, or inflammation near the treatment area

  • have previously experienced a complication from dermal filler

  • have prior filler in the area, particularly if you are unsure what product was used or when it was placed

  • have recently undergone surgery, dental procedures, facial treatments, lasers, microneedling, or other injectable treatments

4. History of cold sores.
If treatment will involve areas near the lips or mouth , chin and you have a history of cold sores or fever blisters, please tell your provider before treatment. Injectable procedures may trigger a recurrence, and antiviral prophylaxis may be considered when appropriate.

5. Alcohol and bruising.
If medically appropriate, consider avoiding alcohol for approximately 24 hours before treatment because it may increase bruising or swelling.

6. Stay hydrated.
Drink fluids normally before your appointment unless you have been instructed to restrict fluids for another medical reason.

7. Reschedule if you are ill or have an active infection.
Please contact Elcin Aesthetics before your appointment if you develop fever, significant illness, dental infection, active cold sore, or infection/inflammation near the treatment area.

After Your Appointment

Do Not Massage Unless We Tell You To

Avoid rubbing, pressing, manipulating, or aggressively massaging the treated area unless your provider specifically instructs you to do so.

Keep the Area Clean

Avoid unnecessary touching of the injection sites.

Use clean hands when applying skincare.

Exercise

Avoid strenuous exercise for approximately 24 hours, particularly if you are experiencing swelling or bruising.

Heat

For approximately 24–48 hours, avoid excessive heat such as:

  • Saunas

  • Steam rooms

  • Hot yoga

  • Very hot showers

  • Hot tubs

Alcohol

Consider avoiding alcohol for approximately 24 hours after treatment, especially if you are prone to bruising.

Skincare

Use gentle skincare while the injection sites are healing.

Avoid irritating products directly over recently treated areas if they sting or cause irritation.

This may include temporarily holding:

  • Retinoids

  • Exfoliating acids

  • Scrubs

  • Strong active skincare

Restart these products once the skin is comfortable and injection sites have healed, or according to your individualized instructions.

Makeup

Avoid applying makeup over open or actively bleeding injection sites.

Once injection sites have closed and the skin is comfortable, makeup can generally be resumed.

If You Have Under-Eye Swelling

You may:

  • Sleep with your head slightly elevated

  • Use a clean, cool compress gently if recommended

  • Avoid applying heavy pressure to the area

  • Avoid rubbing or massaging unless instructed

Allow swelling time to settle naturally.

What to Expect

During Your Appointment

A small amount of blood will be drawn and processed to prepare your PRF.

Depending on the treatment area and plan, PRF may then be injected using a needle or cannula.

You may feel:

  • Pressure

  • Pinching

  • Stinging

  • Tenderness

  • Temporary fullness

Numbing may be used depending on the treatment area and technique.The treated area may initially look more swollen or prominent than the final result.

What to Expect After PRF

Temporary injection-related reactions are common.

You may experience:

  • Swelling

  • Bruising

  • Redness

  • Tenderness

  • Mild soreness

  • Temporary firmness

  • Small bumps at injection sites

  • Mild asymmetry caused by swelling

Published facial PRF/PRP literature generally describes adverse effects as mild and temporary, most commonly bruising, swelling, or injection-site reactions.

Under-Eye PRF

The under-eye area is especially prone to swelling.

You may notice:

  • Puffiness

  • Temporary fullness

  • Bruising

  • Mild tenderness

  • Uneven appearance from swelling

Swelling may look more noticeable in the morning and can temporarily make the under-eye area appear fuller before it improves.

Do not judge your final result during the early swelling period.

When Will I See My Final Result?

PRF works gradually by supporting your body’s natural regenerative processes. You may notice early changes within a few weeks, but improvement can continue to develop over approximately 6–12 weeks as the treated tissue remodels.

For some patients, especially when treating the under-eye area or overall skin quality, the most noticeable result may continue evolving over 2–3 months.

A series of treatments is often recommended, so your final result may depend on the number of sessions completed, treatment area, age, skin quality, and individual response.

I would avoid promising a single exact “final result” date because PRF response varies and the evidence does not support one universal timeline for every patient.

How Many PRF Treatments Will I Need?

After a full consultation , we find most paFor optimal results, we typically recommend starting with a series of 3–4 PRF treatments, spaced according to your treatment plan and the area being treated.

After completing your initial series, many patients choose a maintenance treatment every 6–12 months to help support ongoing skin quality and regenerative goals.

Your ideal treatment schedule may vary depending on your age, skin quality, treatment area, goals, and individual response to PRF.

When Will I See My Final Results?

PRF works gradually. Early changes may be noticeable within a few weeks, with continued improvement developing over approximately 6–12 weeks after treatment.

Because PRF is often performed as a series, your overall result may continue to evolve throughout the course of your treatments and for several months afterward.

Typical plan:
3–4 initial treatments → maintenance every 6–12 months

Please contact Elcin Aesthetics if you have questions about your recovery or experience symptoms that concern you.

When to Contact Us

    • Swelling that is severe, progressively worsening, or not beginning to improve as expected

    • Increasing redness rather than gradual improvement

    • Increasing warmth

    • Increasing or significant pain

    • Pus or unusual drainage

    • Fever or chills

    • A spreading rash

    • Hives

    • Significant or persistent asymmetry after the expected swelling period

    • New blistering or open sores

    • Cold-sore or herpes-like lesions

    • Any unusual skin discoloration

    • Any symptom that concerns you or is worsening rather than improving

    Seek Urgent Medical Attention

    Seek urgent medical evaluation for:

    • Difficulty breathing

    • Severe swelling of the lips, tongue, face, or throat

    • Sudden vision changes

    • Significant eye pain

    • Severe or rapidly escalating pain

    • Marked blanching, dusky discoloration, or other concerning skin-color changes

    • Any severe or rapidly progressing reaction

    Support Your Results at Home

    Your skin may feel temporarily sensitive after treatment.

    A gentle skincare routine can help support the skin while it recovers. Depending on your skin and treatment area, we may recommend:

    • Gentle cleanser

    • Barrier-supporting moisturizer

    • Hyaluronic acid for hydration when appropriate

    • Peptide-containing skincare when appropriate

    • Daily broad-spectrum sunscreen

    Ask us about our recommended post-treatment skincare products and when to restart your normal routine.

Do not wait to hear back from Elcin Aesthetics if you are experiencing vision changes, neurologic symptoms, or another medical emergency. FDA patient guidance specifically identifies vision changes and stroke-like symptoms as reasons to seek immediate medical attention after dermal filler treatment.

Do not wait for a routine office response if you believe you are experiencing a medical emergency. Call 911 or go to the nearest emergency department.

These instructions provide general guidance and do not replace individualized medical advice, informed consent, examination, or instructions given by your treating clinician. Recommendations may vary depending on your medical history, filler product, treatment area, injection technique, and procedure performed.

Complete Your Treatment Plan

PRF can support skin quality, regenerative signaling, and subtle rejuvenation, but it may not address every component of facial aging, pigmentation, volume loss, or muscle movement.

Depending on your goals, your personalized plan may also include:

  • Medical-Grade Skincare — Derma Made
    Support hydration, brightness, pigmentation, texture, and long-term skin health with a customized at-home regimen.

  • Microneedling + PRF
    May be used to target skin texture, fine lines, enlarged pores, acne scarring, and overall skin quality while incorporating PRF into a broader regenerative treatment plan.

  • RF Microneedling + PRF
    May be appropriate when skin laxity, texture, wrinkles, and collagen remodeling are part of your goals.

  • Fractional CO₂ Resurfacing
    May be considered for sun damage, acne scars, fine lines, uneven texture, and more advanced resurfacing needs.

  • Neuromodulators
    Botox® or another neuromodulator may be used to soften dynamic lines caused by muscle movement.

  • Dermal Filler
    May be appropriate when more immediate structural support, contour, or volume replacement is needed.

  • Biostimulators
    Treatments such as Sculptra® or Radiesse® may be considered when broader collagen stimulation or structural support is part of the treatment plan.

  • PRF Hair Restoration

    Did you know that PRF is also able to restore hair loss in some people? learn more: https://care.elcinaesthetics.com/prfhaircare

Maintain Your Results at Home

Ask us about a personalized Derma Made skincare routine designed to support hydration, barrier health, pigmentation, and overall skin quality between treatments.

Not Sure What You Need?

Your treatment plan should be customized — not every patient needs every treatment. Ask us which combination may best support your skin, anatomy, and goals.

Build My Personalized Treatment Plan

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Ask us at your appointment which options may be appropriate for you.

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