Exosomes SKIN and Hair Pre & Post Care Instructions

Exosome-based products contain extracellular signaling components that are being studied for potential applications in skin rejuvenation and hair restoration.

At Elcin Aesthetics, an exosome-based product may be incorporated as an adjunct to selected skin or scalp treatments, such as microneedling or RF microneedling, when clinically appropriate.

For facial treatments, the goal may be to support the appearance of healthier skin, hydration, texture, elasticity and overall skin quality during the post-procedure recovery process.

For scalp treatments, exosome-based products are being investigated as an adjunct to hair-restoration therapies for thinning hair and may be incorporated into a broader plan that includes scalp treatments, PRF and appropriate at-home therapy.

Clinical research is evolving. Results vary, and exosome-based treatment is not guaranteed to produce skin rejuvenation or hair regrowth. Current studies are promising but remain limited by small study populations, differences among products and inconsistent treatment protocols.

Before Your Appointment

Prepare Your Skin or Scalp

ARRIVE CLEAN

For facial treatment, please arrive with clean skin free from:

  • Makeup

  • Sunscreen

  • Serums

  • Creams

  • Oils

  • Self-tanner

For scalp or hair treatment, please arrive with a clean scalp and avoid:

  • Dry shampoo

  • Hair fibers

  • Hairspray

  • Gel or styling products

  • Scalp oils

  • Unnecessary topical products immediately before treatment

2. Pause Retinoids & Strong Exfoliants

To reduce excessive irritation, stop strong exfoliating or sensitizing products before treatment.

A conservative patient-facing recommendation is to avoid for approximately 1 week before treatment:

  • Retinol

  • Prescription retinoids such as tretinoin

  • Glycolic acid

  • Salicylic acid

  • Other AHAs/BHAs

  • At-home chemical peels

  • Physical scrubs or aggressive exfoliating devices

FOLLOW YOUR PROCEDURE-SPECIFIC INSTRUCTIONS

Exosome-based therapy is frequently used as an adjunct to another procedure. Therefore, preparation will depend on whether you are receiving:

  • Microneedling

  • RF microneedling

  • HAIR PRF

  • Another treatment recommended by your provider

The pre-treatment instructions for your primary procedure always take priority.

3. Avoid Waxing & Hair Removal

Avoid waxing, threading, depilatory creams, or other aggressive hair removal on the treatment area for about 7 days beforehand.

4. Avoid Recent Sunburn or Excessive UV Exposure

Do not arrive with sunburned or significantly irritated skin.

Use broad-spectrum sunscreen consistently before your appointment and tell us if you have had substantial recent sun exposure.

5. Tell Us Before Treatment If You Have:

  • An active cold sore or herpes outbreak

  • Open wounds, cuts, or abrasions

  • Active bacterial, viral, or fungal infection

  • Significant skin irritation or sunburn

  • A flare of eczema, dermatitis, psoriasis, or another inflammatory skin condition

  • Recently undergone another aggressive facial treatment

  • Recently started or changed prescription acne or skin medications

  • A known allergy or sensitivity to peel ingredients

  • Any significant change in your health or medications

Treatment may need to be postponed until the skin has fully recovered.

After Your Appointment

IMPORTANT

Your aftercare depends primarily on the procedure performed with the exosome-based product.

Microneedling, RF microneedling and scalp procedures have different recovery requirements.

Always follow the procedure-specific instructions provided by Elcin Aesthetics in addition to this guide.

IMMEDIATELY AFTER TREATMENT

Do not rub, scratch, pick or unnecessarily touch the treated area.

Because recommended contact time and cleansing instructions may vary according to the specific product and procedure, do not wash the treatment area or apply additional products until the time instructed by your provider.

Avoid adding products on your own.

Do not immediately layer:

  • Retinoids

  • Exfoliating acids

  • Scrubs

  • Strong vitamin C preparations

  • Fragranced products

  • Essential oils

  • Unapproved topical treatments

over recently treated skin or scalp.

Use only the products recommended to you during the initial recovery period.

FACIAL TREATMENT AFTERCARE

If your exosome-based product was used with facial microneedling or RF microneedling, you may temporarily experience:

  • Redness

  • Warmth

  • Mild swelling

  • Tightness

  • Sensitivity

  • Dryness

  • Mild flaking or rough texture

These symptoms are often associated with the accompanying procedure itself rather than specifically with the exosome product.

During the initial recovery period:

  • Keep your skincare simple and gentle.

  • Avoid picking or peeling flaking skin.

  • Avoid aggressive exfoliation.

  • Avoid excessive heat.

  • Avoid sauna and steam rooms.

  • Avoid strenuous exercise until permitted by your procedure-specific instructions.

  • Avoid swimming until the skin barrier has recovered.

  • Minimize direct sun exposure.

Once appropriate for your procedure, use a broad-spectrum sunscreen consistently.

SCALP + HAIR AFTERCARE

If exosome-based therapy was incorporated into a scalp treatment:

  • Avoid scratching or rubbing the treated scalp.

  • Avoid picking at treatment sites.

  • Avoid applying unnecessary styling products immediately afterward.

  • Follow your provider's instructions regarding when you may shampoo your hair.

  • Avoid aggressive scalp massage during the early recovery period.

  • Avoid hair coloring, bleaching or irritating chemical scalp treatments until your provider tells you it is appropriate to resume them.

  • we may recommend that you continue treatment at home with serums to continue strengthening the follicle.

Your hair-restoration treatment continues at home.

Your provider may recommend a specific at-home hair or scalp serum as part of your treatment plan.

Use your recommended product exactly as directed and begin or restart it according to the timeframe provided after your procedure.

Hair restoration is a long-term process. In-office treatments should not be viewed as a substitute for evaluating and treating the underlying cause of hair loss when appropriate.

FIRST 24 HOURS

DO:

  • Keep your skin clean.

  • Use a gentle cleanser if instructed.

  • Use a simple, non-irritating moisturizer.

  • Apply broad-spectrum sunscreen as directed.

  • Keep your hands off the treated skin as much as possible.

  • Allow any flaking to shed naturally.

AVOID:

  • Picking, peeling, scratching, or rubbing the skin

  • Strenuous exercise and heavy sweating

  • Saunas

  • Steam rooms

  • Hot yoga

  • Excessive heat

  • Direct prolonged sun exposure

A 24-hour break from strenuous exercise is commonly recommended, with longer avoidance if the skin remains red or irritated.

MAKEUP

For BioRePeel alone, I recommend avoiding makeup for approximately 24 hours, especially if the skin is irritated.

If BioRePeel was combined with microneedling, be more conservative and wait until the skin barrier has settled — typically at least 24 hours and potentially longer depending on redness and sensitivity.

Use clean applicators when makeup is resumed.

SKINCARE FOR THE FIRST WEEK

For approximately 1 week, AND until your skin is fully calm and intact, avoid:

  • Retinol and retinoids

  • AHAs

  • BHAs

  • Glycolic acid

  • Salicylic acid

  • Benzoyl peroxide if irritating

  • Scrubs

  • Exfoliating brushes

  • At-home peels

  • Strong vitamin C if it stings

  • Fragranced or irritating products

Use a gentle cleanser, moisturizer, and broad-spectrum sunscreen.

We advise avoiding acids and retinoids for approximately 7 days.

SUN PROTECTION

Sun protection is essential during your treatment series.

Use broad-spectrum SPF 30–50+ daily and limit prolonged direct sun exposure.

Do not intentionally tan or use tanning beds while your skin is healing.

What to Expect

FACE + SKIN

Immediately after treatment, depending on the procedure performed, your skin may look pink or red and may feel warm, tight or sensitive.

Over the following several days, you may experience temporary dryness, mild flaking or a rough texture while the skin recovers.

Early clinical studies of exosome-based therapies have reported improvements in measures such as:

  • Hydration

  • Elasticity

  • Appearance of fine lines

  • Texture

  • Pigmentation

  • Overall skin appearance

However, study designs and products vary considerably, and long-term evidence remains limited. These outcomes should therefore be viewed as potential improvements rather than guaranteed results.

HAIR + SCALP

Hair restoration develops slowly because hair follicles progress through natural growth cycles.

Published clinical studies of exosome-based hair therapies have reported potential improvements in hair density and/or hair thickness in selected patients, but evidence remains preliminary and treatment protocols are not standardized.

Hair treatment results can be affected by:

  • Cause of hair loss

  • Genetics

  • Hormonal factors

  • Age

  • Follicle viability

  • Nutritional status

  • Medical conditions

  • Medications

  • Severity and duration of hair loss

  • Consistency with home treatment

Exosome-based therapy does not guarantee new hair growth.

Patients with unexplained, sudden, patchy or progressive hair loss may require further medical or dermatologic evaluation.

WHEN WILL I SEE RESULTS?

Results develop gradually and vary from person to person.

For skin rejuvenation, some patients may notice improved hydration and a healthier-looking glow within the first few weeks. Changes in texture, fine lines, elasticity, and overall skin quality may continue to develop over the following 4–12 weeks.

For hair restoration, patience is important. Hair follicles follow a natural growth cycle, so visible changes may take several months. Some patients may notice reduced shedding or improved hair quality within 6–12 weeks, while improvements in fullness or density may take 3–6 months or longer.

Your results will depend on your individual skin or hair concerns, the procedure performed, your underlying hair-loss pattern, and consistency with your recommended at-home regimen.

Exosome-based therapy does not guarantee a specific result or timeline.

When to Contact Us

Please contact Elcin Aesthetics if you have questions about your recovery or experience symptoms that concern you.

When to Contact Us

Mild redness, tightness, dryness, sensitivity, or light flaking can be expected after treatment and should gradually improve.

Contact Elcin Aesthetics if you experience:

  • Redness that is severe or continues to worsen

  • Significant swelling

  • Increasing pain or burning

  • Persistent intense stinging

  • Blistering

  • Open sores or skin breakdown

  • Significant crusting

  • Drainage or pus

  • Increasing warmth or tenderness

  • Fever or chills

  • Significant facial swelling

  • A rash that is spreading

  • New or worsening cold sores

  • Skin discoloration that is persistent or concerning

  • Darkening or lightening of the skin that develops after treatment

  • Any reaction that seems excessive or is getting worse instead of better

Seek urgent medical attention for:

  • Significant swelling of the lips, tongue, face, or throat

  • Difficulty breathing

  • Difficulty swallowing

  • Fainting or loss of consciousness

  • Signs of a severe allergic reaction

Do not wait for a return call from the office if you are having a medical emergency. Call 911 or go to the nearest Emergency Department.

  • Seek Urgent Medical Attention

    Seek urgent medical evaluation for:

    • Difficulty breathing

    • Severe swelling of the lips, tongue, face, or throat

    • Sudden vision changes

    • Significant eye pain

    • Severe or rapidly escalating pain

    • Marked blanching, dusky discoloration, or other concerning skin-color changes

    • Any severe or rapidly progressing reaction

    Support Your Results at Home

    Your skin may feel temporarily sensitive after treatment.

    A gentle skincare routine can help support the skin while it recovers. Depending on your skin and treatment area, we may recommend:

    • Gentle cleanser

    • Barrier-supporting moisturizer

    • Hyaluronic acid for hydration when appropriate

    • Peptide-containing skincare when appropriate

    • Daily broad-spectrum sunscreen

    Ask us about our recommended post-treatment skincare products and when to restart your normal routine.

Do not wait to hear back from Elcin Aesthetics if you are experiencing vision changes, neurologic symptoms, or another medical emergency. FDA patient guidance specifically identifies vision changes and stroke-like symptoms as reasons to seek immediate medical attention after dermal filler treatment.

Do not wait for a routine office response if you believe you are experiencing a medical emergency. Call 911 or go to the nearest emergency department.

These instructions provide general guidance and do not replace individualized medical advice, informed consent, examination, or instructions given by your treating clinician. Recommendations may vary depending on your medical history, filler product, treatment area, injection technique, and procedure performed.

Complete Your Treatment Plan

Your personalized treatment plan may include exosomes along with other treatments to help achieve your goals

Depending on your goals, your personalized plan may also include:

COMPLETE YOUR TREATMENT PLAN:

One treatment does not have to address every concern.

Your skin or hair-restoration plan should be based on your clinical evaluation, anatomy, skin type, scalp health, pattern of hair loss, treatment history and personal goals.

Depending on your individual needs, your provider may discuss other treatment options.

FOR SKIN REJUVENATION

  • Microneedling
    May be considered for concerns such as texture, fine lines, enlarged pores or acne scarring.

  • RF Microneedling
    May be considered when skin texture, laxity or collagen remodeling are treatment goals.

  • PRF
    An autologous option prepared from your own blood that may be incorporated into selected regenerative treatment plans.

  • CO₂ Laser Resurfacing
    For appropriate candidates seeking more intensive resurfacing for texture, photodamage, wrinkles or scars.

  • Sculptra® or Radiesse®
    Biostimulatory injectables may be considered when facial volume, structural support or collagen stimulation are part of the treatment plan.

  • Neuromodulators + Dermal Fillers
    May be appropriate for dynamic wrinkles, facial balancing or volume-related concerns.

  • Medical-Grade Skincare
    Supports the skin between procedures and is an important part of long-term maintenance.

FOR HAIR RESTORATION

  • PRF Hair Restoration
    Uses an autologous platelet/fibrin concentrate prepared from your own blood as part of an individualized hair-restoration program.

  • Scalp Microneedling
    May be incorporated into selected treatment plans.

  • Personalized At-Home Hair Therapy
    Your recommended serum or medically appropriate hair-loss treatment helps continue your program between office visits.

  • Medical or Dermatologic Evaluation
    May be recommended when the pattern or cause of hair loss requires additional evaluation.

Maintain Your Results at Home

Ask us about a personalized Derma Made skincare routine designed to support your skin barrier, hydration, pigmentation, acne control, and overall skin quality between treatments.

Professional treatments can accelerate improvement, but consistent daily skincare and sun protection are essential for maintaining your results.

Maintain Your Results at Home

Ask us about a personalized Derma Made skincare routine designed to support hydration, barrier health, pigmentation, and overall skin quality between treatments.

Not Sure What You Need?

Your treatment plan should be customized — not every patient needs every treatment. Ask us which combination may best support your skin, anatomy, and goals.

Build My Personalized Treatment Plan

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Ask us at your appointment which options may be appropriate for you.

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